Neuroprotective effects of Moringa oleifera leaf extracts
Neuroprotective effects of Moringa oleifera leaf extracts
- 한국축산식품학회
- Food and Life
- 제2022권 제1호
- : KCI등재후보
- 2022.03
- 19 - 26 (8 pages)
This study was carried out to evaluation the neuroprotective effects of Moringa oleifera leaf. The polyphenols myricetin and kaempferol were detected in M. oleifera leaf at 5.44 and 1,157.13 mg/100 g, respectively. M. oleifera leaf ethanol extract (MOLE) reduced oxidative stress (%) more than vitamin C did (90.26%) at 100 and 200 μg/mL (p<0.05). MOLE increased cell viability (%) (p<0.05) and similarly to vitamin C (88.36%). Additionally, the lactate dehydrogenase (LDH) release into the medium (%) induced by ascorbic acid (vitamin C) was comparable to that of MOLE at 100 and 200 μg/mL (p>0.05). The antioxidant activities of M. oleifera leaf water extract (MOLW) and MOLE were measured. MOLE showed higher 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging (%) and malondialdehyde inhibition (%) than MOLW did (p<0.05). In conclusion, M. oleifera leaf extracts, especially MOLE could be potential natural neuroprotective agents to substitute synthetic chemicals.
Introduction
Materials and Methods
Results and Discussion
Conclusion
Conflicts of Interest
Acknowledgments
Ethics Approval
Author Contributions
Author Information
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