Background: Mixed Reality (MR) is an immersive technology, which has been recently implemented into medicine, recognising its advantageous interactive holograms. VSI HoloMedicine (VSI), MR software running on HoloLens2, Head-Mounted Display (HMD) is an example of this. It has been used in different medical specialities but not extensively in Trauma and Orthopaedics (T&O). Purpose: This review discusses the potential use of VSI in T&O. Study design: Narrative literature review Methods: Keywords were searched for on PubMed and Scoups databases. Reviews and non-English journals were excluded. Results: Full-text screening led to 9 papers being included. Six papers looked at 3D-rendered holograms, superimposing them on patients, displayed via HoloLens2 for surgeries. 3D-rendered holograms in surgeries aid in complex preoperative preparation, and intra-operative navigation. Two journals used HoloLens2 to present medical imaging rendered in 3D holograms to the patients for educating them on medical conditions and interventions they are undergoing. Patients educated with medical imaging presented by 3D-rendered holograms showed deeper understanding. One paper assessed the effectiveness of VSI for medical training. Conclusions: Use of MR software particularly VSI in T&O is not extensively studied. Based on the evidence showing advantages of using MR software, more studies targeted to T&O should be conducted. This innovative tool shows great potential for future development and benefit in the speciality.
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