Objectives: The objective of this study is to assess weight change and examine adverse events in postpartum overweight and obese women with Gamitaeeumjowee-tang for weight loss. Methods: In this retrospective chart review, 53 postpartum overweight and obese women (body mass index, BMI≥23 kg/m2) were medicated with Gamitaeeumjowee-tang for 12 weeks to achieve weight loss. We followed up body composition among these women such as weight, skeletal muscle ratio, body fat mass and BMI changes before and after the program. Adverse events were examined by causality, severity and system-organ classes. Results: A total of 53 patients were included in this study. Postpartum women experienced an average total weight loss of 7.25±2.96 kg (P<0.001), with an average weight loss rate of 10.11±3.85% (P<0.001). Following the 12-week program, there was a significant reduction in body fat rate (5.48±2.52%p) (P<0.001) and a significant increase in skeletal muscle ratio (3.07±1.37%p) (P<0.001). In the comparison according to the postpartum period, both the groups under 6 months and over 6 months significantly decreased in weight and body fat mass. There was no significant difference in weight loss between the groups. However, the group over 6 months showed significantly higher body fat reduction compared to the group under 6 months. No serious adverse events were reported. Conclusions: This study demonstrated that using Gamitaeeumjowee-tang for weight management could be an effective method for losing weight in postpartum overweight and obese women regardless of the postpartum period without causing serious adverse events. Further well-designed prospective studies are needed.
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